Sciclone® ALH 3000 Workstation The Sciclone ALH 3000 Workstation from Caliper brings together over two decades of lab automation and liquid handling expertise, providing life scientists with one of the most versatile, state-of-the-art liquid handling workstations available today.

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With its unique open and modular design, unrivaled liquid handling capabilities, and many added functionalities, the Sciclone ALH 3000 workstation automates a wide array of research and diagnostic applications, from Genomic and Proteomic Sample Preparation to Bio-Molecular and Cell Based Screening Assays.

Powerful, yet easy-to-use software provides excellent liquid handling control, and facilitates the use of multiple options and accessories to enable the full automation of protocols. Among these are three interchangeable 96/384 pipetting heads covering a volume range from 100 nanoliters to 200 microliters, an independent 8 channel pipettor for single well access, and bulk reagent dispense modules for efficient reagent broadcasting. Added accessories such as the Sciclone Gripper, microplate shaker, positive pressure filtration system, temperature controlled locators, and more allow true walk-away automation.

The modular design of the Sciclone enables numerous combinations of pipetting options and accessories to perfectly meet the needs of a given application, and should the unit be required to support multiple applications, or if demands on the unit change over time, it can be easily reconfigured to meet those changing needs.

The highly adaptive nature of the Sciclone in combination with its robust industrial-grade components ensures customers their investment will pay dividends for many years to come.

• State-of-the-art liquid handling performance with excellent reproducibility
• A complete liquid handling workstation that enables the full automation of many different life science protocols
• Outstanding modularity and scalability that enables your investment to grow with you over time, as your needs evolve
• The ability to provide 96 and 384 channel pipetting, plus single well access through an independent 8-channel pipettor, plus bulk reagent dispensing all in one configuration, eliminating the need for multiple liquid handling devices.
• The ability to easily attach subsets of disposable tips, including rows and columns for both row-wise and column-wise serial dilutions
• Swap-on-the-fly pipetting arrays that enable switching between 96 or 384 well pipetting, as well as fixed tips or disposable tips, all within one uninterrupted protocol
• An integrated bulk dispense capability enabling more efficient assay assembly, greater speed, throughput, and improved assay performance
• An integrated gripper that offers 100% grip confirmation, and can hold a plate-lid while the instrument simultaneously carries out pipetting operations.
• And much more...

• Three interchangeable multi-channel pipetting modules
  • ALH-HV module - 96 channel disposable tips, 1-200ul
  • ALH-LV module - 96 or 384 channel, fixed or disposable tips, 0.5 Ð25ul
  • ALH-NL module - 96 or 384 channel, fixed tip, 0.1-5ul
• Z-8 pipettor module with eight independent channels for single well/tube access
• Bulk reagent dispense modules for efficient reagent broadcasting
• Multiple 96 and 384 pipetting arrays
• Automation certified pipette tips
• Microplate shaker
• Ultrasonic wash station
• On-line fill reservoir
• Temperature controlled locators
• Foil plate piercing array
• Positive pressure filtration system
• 1536 deck locators
• iBlock™ table
• Other standard and custom accessories

• Plate replication and reformatting
• Bio-molecular and cell based screening assays
• ADMET Screening
• ELISA's

• DNA/RNA extraction and purification
• PCR/Sequencing set-up and clean-up
• SNP Mapping
• Protein fractionation
• Protein digestion and MALDI spotting
• Protein crystallization
• Yeast-two hybrid assays

Bilden visar Z8 optionen, 8 individuella pipetter med den mest avancerade vätskenivådetektering på marknaden. till höger skymtar bulkdispensorn, använd upp till 6 inidviduella vätstskor som dispenseras via 8 kanaler för reagenstillsättning m.m.

8 individuella vätskekanaler , 6 bulkdispensor för reagens & buffert monterad, 96 eller 384 pipetterings array= 3 instrument i ett. Denna funktionalitet på en liten yta är oöverträffad. 120*75*100 cm.

Sciclone kan byta pipetteringsverktyg under drift. Du kan arbeta i de vanliga formaten 96/384/1536 med teflonbelagda stålspetsar, engångspipetter eller pintools. Varför köpa en ny robot när dina assayer förändras ? Byt pipetteringsverktyg istället. Titta på filmen här.

Bilden ovan visar olika pipetteringsverktyg 96/384/1536 i ett utförande med teflonbelagda stål tips, De finns naturligtvis som disposable tips utförande också. Sciclone ALH 3000 erbjuder stor flexibilitet och framtidssäkring av sin investering.

Vill du byta volymområde från 50nL-0.5uL till 0.5uL-25 uL till 1 till 200uL ? Inga problem, lossa 4 skruvar och en kontakt och montera en ny pipetteringsmodul och du kan fortsätta efter 5 minuter utan hjälp från servicetekniker. Varför skall man köpa en ny robot när man vill ändra volymintervallet ?

Förvara dina pipetteringsmoduler för olika volymområden på ett betryggande sätt.

Sciclone ALH 3000 har ett stort arbetsbord med 20 positioner för microtiterplattor. Använd platthanteringsroboten TwisterII för att skapa 'walk - away ' tid i systemet. TwisterII sörjer för för förflyttning av plattor mellan olika steg i assayen och magasinering av färdiga plattor. Du kan integrera mer än 200 populära instrument till Sciclone/TwisterII för att bygga upp helautomatiserade system. Sciclone har också en integrerat gripdon för för förlyttning on-deck.

Sätt in externa instrument under/bakom TwisterII stora integrerade system.Titta på tänkbara konfigurationer här

Bruce Roe, Head of advanced center for genome technology

Requirements: Efficient ultrapure DNA prep with minimal intervention

Results: “…7,680 templates in 3 hours, 384 well format and 4¢ a prep”
READ then complete article here download the PDF file here